Difflam™ 3% Cream

Difflam™ 3% Cream is a topical analgesic and non-steroidal anti-inflammatory agent.

  • Available in two sizes, 35gm and 100gm
  • Suitable for adults and children of all ages1
100g Difflam™ 3% Cream

For the relief of symptoms associated with painful inflammatory conditions1,2

Use Difflam™ 3% Cream for the relief of symptoms associated with painful inflammation associated with conditions such as myalgia and bursitis and including traumatic conditions such as:

  • Sprain
  • Strains
  • Contusions
  • Sore muscles
  • Stiff joints
  • After-effects of fractures

How it works

Difflam™ 3% Cream is well absorbed through the skin and has been shown to have anti-inflammatory and local anaesthetic actions1, unlike cooling gels and heat patches that work by only cooling or heating the skin. The application of benzydamine to the skin produces slow and prolonged penetration through the tissue.2

The active ingredient within the cream, benzydamine, works by reducing the locally induced inflammation, oedema, and granuloma formationi, it also demonstrates antipyreticii antiexudativeiii activities.2 It also exhibits analgesic properties if pain is caused by an inflammatory condition and local anaesthetic activity.1

Product dosage information

Adults, children of all ages

The cream should be massaged lightly into the affected area and applied three times a day, (and at the discretion of the doctor up to six times daily in more severe conditions).1

The topical application of Difflam™ 3% cream, 3 times daily for 6 days in 50 patients with soft tissue injuries, led to a significant improvement in pain relief, tenderness, erythema, functional impairment and swelling compared to placebo on day 6.1

Overall, benzydamine was well tolerated in clinical trials.1

Difflam™ 3% Cream has been clinically tested as a short-term treatment for the relief of symptoms associated with painful inflammatory conditions of the musculo-skeletal system including myalgia and bursitis. Further, it showed clinical benefit in traumatic conditions such as sprains, strains, contusions and post fractures (Diebschlag 1985; Haig 1986; Chatterjee 1977). Difflam™ 3% Cream is well absorbed through the skin and has been shown to have anti-inflammatory and local anaesthetic actions.1

Do not use Difflam™ Cream if you are allergic to Benzydamine Hydrochloride or any of the other ingredients listed in the Patient Information Leaflet.

Always read the label. Do not use for more than seven days continuously unless under advice from a healthcare professional. Avoid contact with eyes. Keep medicines away from children.

Always use Difflam™ Cream exactly as instructed, and check with a healthcare professional if you are not sure. If your symptoms get worse or do not improve, contact your doctor, pharmacist or dentist.

References

  • Difflam™ 3% Cream or Difflam-P 3% Cream Summary of Product Characteristics (May 2016).
  • Quane PA et al. Inflammopharmacology. 1998; 6: 95-107.

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